Частота мікроальбумінурії у хворих на гіпотиреоз
DOI:
https://doi.org/10.24026/1818-1384.4(41).2012.86009Ключові слова:
hypothyroidism, microalbuminuria, the risk factorsАнотація
The purpose of research – the study of the frequency and magnitude of microalbuminuria (MAU) in patients with primary hypothyroidism, the establishment of the degree of relationship of microalbuminuria with major risk factors. Under supervision were 58 patients (12 men and 46 women) with primary hypothyroidism. The frequency of microalbuminuria in patients with hypothyroidism reaches 46.6%, depending on the duration of the disease, being in the range of 16.7% to 57.6%. Likelihood of microalbuminuria increases with systolic and diastolic blood pressure. There was a significant correlation between the level of blood pressure and pulse rate of microalbuminuria detection (p = 0.045). The prevalence of microalbuminuria in patients with hypothyroidism increases with the presence of diastolic dysfunction of the left ventricle. Correlation relationship MAU values and indicators of thyroid function, and lipid profile in patients with hypothyroidism is not established.Посилання
Балаболкин М. И., Клебанова Е. М., Креминская В. М. Фундаментальная и клиническая тироидология: Руководство. – М.: Медицина, 2007. – 816 с.
Andersen N.H. Decreased left ventricular longitudinal contraction in normotensive and normoalbuminuric patients with Type II diabetes mellitus: a Doppler tissue tracking and strain rate echocardiography study. / N.H. Andersen, S.H. Poulsen, H. Eiskjer et al. // Clinical Science. – 2003. – Vol. 105. – P. 59-66. https://doi.org/10.1042/cs20020303
Cirillo L. Definition of kidney dysfunction as a cardiovascular risk factor. Use of urinary albumin excretion and estimated glomerular filtration rate / L. Cirillo, P. De Santo, D. Mancini et al. // Arch. Intern. Med. – 2008. – Vol. 168, №6. – P. 617-624. https://doi.org/10.1001/archinte.168.6.617
De Zeeuw D. Microalbuminuria as an early marker for cardiovascular disease / D. De Zeeuw, H.H. Parving, R.H. Henning // J. Am. Soc. Nephrol. – 2006. – Vol. 17, №8. – P. 2100-2105. https://doi.org/10.1681/asn.2006050517
Hillege H.L. Microalbuminuria is common, also in a non-diabetic, non-hypertensive population, and an independent indicator of a cardiovascular risk factors and cardiovascular morbidity / H.L. Hillege, W.M. Janssen, A.A. Bak et al. // J. Intern. Med. – 2001. – Vol. 249. – P. 519-526. https://doi.org/10.1046/j.1365-2796.2001.00833.x
Sarafidis P.A. Microalbuminuria and chronic kidney disease as risk factor for cardiovascular disease / P.A. Sarafidis, G.L. Bakris // Nephrol. Dial. Transplant. – 2006. – Vol. 21, №9. – P. 2366-2374. https://doi.org/10.1093/ndt/gfl309
Shin D.H., Lee M.J., Kim S.J. Preservation of renal function by thyroid hormone replacement therapy in chronic kidney disease patients with subclinical hypothyroidism // The Journal of Clinical Endocrinology and Metabolism. – 2012. – June 20 [Epub ahead of print]. https://doi.org/10.1210/jc.2012-1663
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