Роль кишкової мікробіоти у розвитку ожиріння та інсулінорезистентності

С. М. Ткач, О. С. Тимошенко, А. А. Дорофеєва

Анотація


В огляді описано взаємозв’язок між дисбалансом кишкової мікробіоти та розвитком ожиріння, інсулінорезистентності (ІР). Показані метаболічні, імуногенні ефекти кишкової мікробіоти на організм в цілому, особливості її складу та поділ на «ентеротипи», патогенетичні механізми впливу на хронічне системне запалення, що супроводжує ожиріння та ІР. Представлені види модифікації кишкової мікробіоти як один з методів профілактики та лікування багатьох захворювань, в тому числі ожиріння та ІР.


Ключові слова


кишкова мікробіота; ожиріння; інсулінорезистентність

Повний текст:

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Посилання


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DOI: https://doi.org/10.24026/1818-1384.1(53).2016.75590

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