Гіпертрофія лівого шлуночка у хворих на активну акромегалію: клініко-біохімічні та клініко-гормональні кореляти
DOI:
https://doi.org/10.24026/1818-1384.1(46).2014.75332Ключові слова:
acromegaly, left ventricular hypertrophy, growth hormone, insulin like growth factor 1Анотація
Examined 76 (26 men and 50 women) patients with active acromegaly aged from 20 to 70 years, average age 48.22±12.19 years. Echocardiographic signs of hypertrophy of the left ventricular (LVH) revealed in 63.2% of patients, including 46.0% – concentric LVH. Found that high levels of pituitary growth hormone (GH) and insulin like growth factor-1 (IGF-1) were independent predictors of LVH. Influence of GH and IGF-1 on the formation of LVH mediated through anthropometric parameters and levels of systolic and diastolic blood pressure, which are predictors in patients with acromegaly LVH.
Посилання
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