До питання про формування інсулінорезистентності у підлітковому віці
DOI:
https://doi.org/10.24026/1818-1384.2(23).2008.118475Ключові слова:
insulin resistance, index HOMA-IR, cortisol, leptin, adolescent boysАнотація
System analysis of some hormonal effects on insulin sensitivity in adolescent boys of 11-17 ages was done. It was determined that insulin resistance index HOMA-IR=3.9 divides sample on sensitive and resistant to insulin individuals. It was shown selective effects of some hormones on insulin stimulated glucose disposal by target tissues: cortisol increases threshold of hepatocytes sensitivity; high concentration of leptin inhibites postprandial glucose uptake by muscles and adipose tissue.Посилання
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