Діабетичний гастропарез: епідеміологія, механізми розвитку, сучасні підходи до ведення хворих

С. М. Ткач

Анотація


В огляді розглянуто сучасні дані відносно епідеміології, патофізіології, природного перебігу, діагностики та лікування гастропарезу, в першу чергу – діабетичного. Наявні дані стосовно високої розповсюдженості діабетичного гастропарезу та його значного впливу на наслідки та якість життя хворих вимагають оптимізації ведення хворих з цією патологією У хворих на цукровий діабет гастропарез погіршує нутритивний статус та глікемічний контроль, чинить негативні вторинні ефекти на органи, що може підвищувати смертність. Перша лінія лікування полягає в модифікації дієти, застосуванні таких медикаментів як протиблювотні засоби та прокінетики. Друга лінія лікування передбачає проведення електростимуляції шлунку або хірургічного втручання. Серед нових терапевтичних стратегій розглядають застосування нових прокінетиків без побічних кардіоваскулярних ефектів, агоністів греліна, стовбурових клітин.

Ключові слова


гастропарез; діабет; лікування

Повний текст:

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Посилання


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DOI: https://doi.org/10.24026/1818-1384.2(58).2017.105532



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